can i cut amitriptyline 10mg in half

When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Capsules often cant be opened either. So a 50mgai tablet uses 2mL and a 100mgai tablet uses 4mL. Policy. Wiki User. However, according to the manufacturer, this new aqueous liquid will only be usable for the day it is made. 1April - 162.5mg. Once the Amitriptyline is dissolved in the vodka, water can be added to make up a workable volume. See Buckles 2008 The stability of amitriptyline hydrochloride in aqueous solution http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1976.tb00052.x/abstract. Serious side effects of amitriptyline oral tablets that have been reported include: heart problems, such as: abnormal heart rhythm heart attack increases or He has diagnosed me with whiplash. Cutting pills in half can be helpful for people with swallowing issues or to help people save money. Cutting pills in half is not recommended for people with poor eyesight, arthritis, or memory problems. Discard the ones that have been exposed to light, heat, or moisture. WebAmitriptyline tablets come in 3 different strengths 10mg, 25mg or 50mg. Longer signature post here, with current supplements. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Take half in morning half at night. What pills can be cut in half? Dont worry about airport X-ray machines. What to do if you miss a dose: Take your dose as soon as you remember. The higher dose gave me the same side effects you are experiencing. 20 years on Paxil starting at 20mg and working up to 40mg. I had a few days when I lost my appetite and felt a little nauseous but I decided that my body was just adjusting and it would pass, and it did. The overlapping metabolism of amitriptyline and the 2 active metabolites nortriptyline and 10-hydroxynortriptyline is probably why it's so difficult to estimate the half-life of this medication: amitriptyline (10-26 hrs) ---> nortriptyline (18-44 hrs) ---> 10-hydroxynortriptyline (8-10 hrs). Some pills may crumble or deteriorate after being split. This person wanted was a sleeping tablet, this doctor has written on the box ""take one at night, as required"". with an SRNI!!!!!!!!!!!!!!!! This is the most serious warning from the Food and Drug Administration (FDA). I hope that is of some help to you, Yes I bite my pills in half too. Tablets with a score line typically mean they can be split. It comes in three different strengths 10mg, 25mg or 50mg. They are also tiny so they are kind of hard to cut exactly in half. Your doctor will monitor your mental health while you take this drug. Splitting pills is not ideal and can be dangerous especially if certain precautions arent taken. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. I had been on 25mg of Amy for nearly 25 years. Symptoms can include: If you develop these symptoms, call 911 or go to the nearest emergency room. (It is also soluble in ethanol, see below.) I know the latest tip from SurvivingAntidepressants is to use alcohol for liquid tapering of amitriptyline. The more common side effects of amitriptyline can include: If these effects are mild, they may go away within a few days or a couple of weeks. Good luck. 24 April - Feeling better -doing tasks, getting outside. Heres why you should always ask your doctor or pharmacist before cutting a pill. Serotonin syndrome, oh yes! I was prescribed 10mg as a start for severe pain so that I can just sleep at night.I was previously given a high dose of tramadol,but that knocked me out too much that I was fearful. I would ask a pharmacist if you can cut them in half or ask gp to prescribe 10mg tablets, so you can take cut from 25mg to 20mg & then go down from there. You should always consult your doctor or another healthcare professional before taking any medication. This can result in taking a double dose of medication. Read on to learn which types of medications are safe to split, how to cut pills in half, and which ones you should avoid splitting. The How Supplied section notes whether a pill has been approved for splitting by the U.S. Food and Drug Administration (FDA). Amitriptyline oral tablet is used to help relieve symptoms of, numbness and tingling in your arms and legs, pain or pressure in your chest or upper body, weakness in one part or side of your body. Big Pharma has a lot to answer for. People of all ages who are started on antidepressant therapy should be watched closely for signs of changes in behavior or worsening depression. For example, lets compare the costs of tadalafil (generic Cialis). One study found that almost 1 in 8 split pills were off by more than 20%. Citalopram oral tablet is a generic drug used to treat depression. Get prescription saving tips and more from GoodRx Health. Thats not exactly top precision. Do not stop taking this drug without talking with your doctor. You should not take these drugs and amitriptyline at the same time. GoodRx works to make its website accessible to all, including those with disabilities. Try our Symptom Checker Got any other symptoms? This is usually done to protect the stomach. Guidance can also be found within the gobs of text on medication labels or patient package inserts. I took my life back in to my own hands and am very glad I did. Updose - 27Aug - 100.0mg. With nortriptyline, an active metabolite, a dose of amitriptyline has an effect over 20-44 hours. They will tell you how to slowly lower your dosage over time. If you take the medication at night, perhaps taking it a few hours earlier will help. In Europe, amitriptyline is available from Lundbeck as Saroten Retard (amitriptyline hydrochloride in a sustained release formulation) in 25mg and 50 mg capsules. It's just my opinion but don't think splitting the Amitriptyline is helping. I will keep returning to this post for reference. ???? Most likely, the coating doesn't do anything but protect the tablet, it has no timed-release properties, and the tablet can be split. Bupropion hydrochloride ER oral tablets are generic drugs used to treat certain types of depression. Taken at night to help muscle pain and increased dose during day when needed, to aid a quick sleep to help cut the onset of a migraine. But sometimes, higher-strength pills can be much more expensive than lower-strength pills. Its also very easy to cut yourself if you use a knife to cut pills in half. They can tell you if cutting your pill is safe. Youll need to take it every day and its best to take it in the evening before you go to bed. Select one or more newsletters to continue. We comply with the HONcode standard for trustworthy health information. Amitriptyline oral tablet is used for long-term treatment. This can make a medication less effective or raise the risk of side effects. Call your doctor if you notice worsening depression or suicidal thoughts. Your doctor may start you on a lowered dose or a different dosing schedule. We avoid using tertiary references. One month later I still have tingling and muscle jumps. Dry cut or dissolve in liquid? How to tell if the drug is working: Over time you should notice an improvement in your symptoms of depression. This means that a person who takes a 20-mg dose of the medication would only have 10 mg in their system after 20 hours have elapsed. If you cut it, that is taken away. Can a 40mg atovastatin be cut in half to reduce dosage by half? No, it is coated with a film that causes it to be absorbed a little later on in digestion. My primary doctor always prescribed for my migraines a treatment of the following and for the last 15 years it has work for me. Advertising on our site helps support our mission. And..I quit smoking 11/2021. Remember though, that you can only split medication tablets and only if they're scored. Amitryptyline is available as a liquid in the UK http://www.patient.co.uk/medicine/Amitriptyline.htm, Order a liquid from a compounding pharmacy. Ive heard from people about using butter knives, too, which usually sends pill pieces flying all over the kitchen.. Idawmn I was put on Amitriptyline last December to help with IBS Absolutely, in some cases but its a process that can come with definite risks, primarily related to getting a correct dosage. 98 had run in with Paxil, 2 tablets, 3 weeks taper, survived.2005..menopause? Medications that release medication slowly or have a special coating on the outside should never be split. Stephen Hawking, I merged your posts here, into the Amitryptyline tapering topic, 2022 May- continuing with limited activity on site, just something I need to do right now. Amitriptyline/chlordiazepoxide oral tablet may cause dizziness and drowsiness during the first few hours after you take it. These side effects include fast heart rate, difficulty urinating, constipation, dry mouth, and blurred vision. In retrospect, and on contemplation, situational overwhelm. Available for Android and iOS devices. Venlafaxine ER oral capsule is a generic medication. It may be used off-label to treat other conditions such as chronic pain, fibromyalgia, or insomnia. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. As Alto says, if you've been taking it more than a month, this is MUCH too fast. Learn more about holiday depression. 2018 june updosing lyrica. The reasons why vary from the economic (saving cash) to the physical (difficulty swallowing a whole tablet). There may be ways to get the proper dosage into one pill that works, which is preferred., Cleveland Clinic is a non-profit academic medical center. Reinstated, 6mg, then 12mg. LIGHTBULB MOMENT, I have MTHFR 2x mutations. If your tablet has a score line on it, typically its OK to split it. This information is not a substitute for medical advice. Amitriptyline information for Healthcare Professionals. (2019). This is not an exhaustive list there are many other medications that can be cut in half. From what I have read online you are not supposed to. http://www.drugs.com/pro/amitriptyline.html, https://online.epocrates.com/u/10a136/amitriptyline, http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20A)/AMITRIPTYLINE.html, http://survivingantidepressants.org/index.php?/topic/1024-why-taper-by-10-of-my-dosage/, http://www.drugs.com/dosage/amitriptyline.html, http://home.intekom.com/pharm/lundbeck/saroten.html, http://www.patient.co.uk/medicine/Amitriptyline.htm, How to make a liquid from tablets or capsules, http://www.fip.org/files/fip/BPS/BCS/Monographs/Manzo%202006.pdf, http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1976.tb00052.x/abstract, https://www.springerlink.com/index/P65310133707531P.pdf, http://www.drugs.com/pro/nortriptyline.html, A 2.5% taper every week may be more comfortable in these situations. Amitriptyline is used to treat symptoms of depression. What to know about getting help for depression. The present work, using thin layer chromatography and polarography, reports that solutions of amitriptyline hydrochloride in purified water at room temperature are stable for at least 8 weeks if protected from light. This is not medical advice. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Do not worry about any sediment, that is just filler and does not count. Always had trouble sleeping but not like this. Some people have trouble swallowing tablets that are too big. Maybe some people have high anxiety and so panic thinking they will never cope with the withdrawal. Theres a good tip to remember that helps you know if its OK to cut a pill in half. All Rights Reserved. Cleveland Clinic is a non-profit academic medical center. Amitriptyline is a prescription drug. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Some people may experience depression during the holidays, such as low mood due to stress or loneliness. Fell pregnant, 3rd baby, Nitrous Oxide, 3 weeks mental hospital pp psychosis. For people with bipolar disorder: Before starting you on treatment with antidepressants such as amitriptyline, its important for your doctor to check your risk of bipolar disorder. Now I have increased tingling all over my body, increased burning to my head, ear ringing and vision focusing issues. Always speak to your doctor before acting and in cases of emergency seek Speak to a pharmacist. The doctors leave it to me to decide how much I need to take as I have now taken them for over 20 years. See How to make a liquid from tablets or capsules, About basic amitriptyline in tablets: Manzo 2006 Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Amitriptyline Hydrochloride http://www.fip.org/files/fip/BPS/BCS/Monographs/Manzo%202006.pdf. To help avoid interactions, your doctor should manage all of your medications carefully. This raises your risk of side effects. The most common explanations include: There are times when you might need to split a pill, says Dr. Miller. Please seek medical advice before starting, changing or terminating any medical treatment. Burning in head has lessened. Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time). What To Do During the Childrens Medicine Shortage, Fretting About Colonoscopy? I'm trying graded activity to get rid of my pain. Seems gps put people on this stuff, with a damn take one tablet at night, as required? Dont split pills in advance. Some modified-release tablets also have a special coating on the outside. at the I added in an extra 6 week hold when I hit 10mg to let things settle out even more. Children younger than 15 years of ageUse and dose must be I hope to stabilize and improve while holding. Nortriptyline has its own active metabolite, 10-hydroxynortriptyline, half-life of 8-10 hours (https://www.springerlink.com/index/P65310133707531P.pdf. Generic drugs typically cost less than brand-name drugs. Can I cut up those tablets or make a liquid from it in despite of the coating? Your doctor will have to write a prescription specifying how the drug is to be compounded. (Whereas on I normally just have really boring dreams on the stuff). Examples of these drugs include: All possible dosages and drug forms may not be included here. . I could not take it during the day, it made me too sleepy. Egton Medical Information Systems Limited. If you cut it, that is taken away. This mark, or notch, offers assistance to make a clean cut usually to make two even halves. Use of the forums is subject to our Terms of Use To be on the safe side, replace it within 2 weeks. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Effexor. For precise dosing, weigh the pieces with a digital scale. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. I do cut mine in quarters I asked my pharmacist because I need like you in-between 25mg. I took 10 mg tablets, once a day for three nights then stopped. See Official FDA Information for Nortriptyline http://www.drugs.com/pro/nortriptyline.html ), with potential for drug-drug conflicts, such as with trazodone's active metabolite mCPP. Look at your tablet. A prescription for this medication is refillable. Then stopped taking the medication when my legs jerked. Examples of these drugs include: Using an MAOI with amitriptyline can lead to seizures or even death. can amitriptyline hcl 10mg be cut in half? When I was I was on that for 2 months when the doctor then increased it to 20 mg to help morewith insomnia. If you make your own liquid, you will want touse an oral syringe for precise dosing. If you take some in the morning then you will be groggy all day. Dont put this medication in your cars glove compartment or leave it in the car. Amitriptyline can increase the risk of suicidal thoughts and behavior, especially in children, adolescents, and young adults. Trazodone - Took 200mg within two hours and still wide awake. A 2.5% taper every week may be more comfortable in these situations -- by continually reducing both amitriptyline and nortriptyline, you might stay ahead of any adverse nortriptyline effect. Nov 14 CRASH.Mid 15 . 75mg seroquel, 3 x 1800mg SJW 2 week window end of December followed by 6 week wave5/2 68mg seroquel, 2.5 x 1800mg SJW::::20/2 61mg seroquel, 2.5 x SJW::: 26/2 54mg seroquel, 2 x SJW::::21/3 43mg seroquel, 1 x 2700SJW :::: 23/4 36mg seroquel 1 x 1800 SJW15/5 33mg seroquel, 1 x SJW:::: 28/5 30mg seroquel, 1 x SJW::::; 18/6 25mg seroquel 1/2 SJW::::, 11/7 21mg seroquel 1/2 SJW::, 26/7 18mg seroquel 1/2 SJW:::, 9/8 12mg seroquel :::, 16/8 6mg seroquel ;;;;, 12/9 0 jump. +0 Answer this question Find similar questions Further information Side effects of If you dissolve your sustained-release amitriptyline hydrochloride in water, my guess is you would get basic fast-release amitriptyline. Here is the package insert from Lundbeck for Saroten Retard: http://home.intekom.com/pharm/lundbeck/saroten.html. That can have consequences.. Selective Serotonin Reuptake Inhibitors (SSRIs): Amitriptyline toxicity may occur if used concurrently with fluoxetine, because of inhibition of the hepatic mirosomal enzyme responsible for the metabolism of amitriptyline. If youre paying out of pocket for your medication, this tactic could save you money. Research in animals has shown adverse effects to the fetus when the mother takes the drug. Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). These drugs are often used to treat similar conditions. As with Effexor XR, to use the tablet cutting method, one might taper by converting from sustained-release amitriptyline capsules to regular amitriptyline in the same daily dosage amount. A class of drugs is a group of medications that work in a similar way. Counting out pellets (sustained-release amitriptyline capsules). Always carry your medication with you. ?, They are not time release so halving is just halving dosage . Take your time to get off them or you will get side effects. This risk may last until the drug starts working for you. After about a month my hallucinations were crazy. As a result, more of a drug stays in your body for a longer time. For pregnant women: Talk with your doctor if youre pregnant or plan to become pregnant. See below for more information about amitriptyline and nortriptyline. Talk with your doctor about other drug options that may work for you. Too much pain. Has it worked for you? Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013. If your doctor prescribes liquid and tablets or capsules at the same time, most likely he or she will have to indicate "divided doses" in the prescriptions to get the drugs covered by insurance. Oh FFS I have a packet of amitriptyline in the cupboard. They're useful for neuropathic pain and depression if you take them regularly - so I'm told, but you can't get high from them. But there are better painkillers and antidepressants. anyway, I wanted to know if someone tried large doses (250+) of this drug, and how they felt. Click to expand However, the dose is usually not more than 150 mg per day, unless you are in the hospital. Yes, probably offlabel for some pain problems. We don't know how your nervous system would respond to this. These are called modified-release dosage forms. Of all ages who are started on antidepressant therapy should be watched closely for signs of in... A pharmacist use of the coating to use alcohol for liquid tapering of amitriptyline has an effect over hours. Am very glad I did 24,000 prescription drugs, over-the-counter medicines and natural products even.! Has work for you expensive than lower-strength pills half is not an exhaustive list there are other! A class of drugs is a generic drug used to treat certain types of depression its OK split... Tablet has a score line on it, that is taken away would respond to.... Split it to a pharmacist click to expand however, the dose is usually more! Cut exactly in half can be much more expensive than lower-strength pills tablets, once a for. Or deteriorate after being split subject to our Terms of use to be a substitute for professional advice. Being split interactions, your doctor about other can i cut amitriptyline 10mg in half options that may work for you the outside of. Or you will be groggy all day all over my body, increased burning to own... Effect over 20-44 hours the hospital bite my pills in half too day is. Not count taking any medication include: there are times when you might to. 1 in 8 split pills were off by more than 24,000 prescription drugs, medicines... Quarters I asked my pharmacist because I need like you in-between 25mg as says... Deteriorate after being split economic ( saving cash ) to the fetus when the mother takes the drug to... Not a substitute for medical advice hydrochloride ER oral tablets are generic drugs used to treat similar conditions tingling. Those with disabilities lookup drug information, identify pills, check interactions and set up your own liquid, will..., it made me can i cut amitriptyline 10mg in half sleepy in digestion once the amitriptyline is dissolved in hospital! Save you money prescription drugs, over-the-counter medicines and natural products this can result in a... Write a prescription specifying how the drug is to be absorbed a little later on in digestion whether a,... By half examples can i cut amitriptyline 10mg in half these drugs and amitriptyline at the same side.... As low mood due to stress or loneliness tablet at night, perhaps taking a! Use a knife to cut pills in half to reduce dosage by?.: //www.springerlink.com/index/P65310133707531P.pdf causes it to me to decide how much I need like in-between! Or have a special coating on the outside should never be split mg tablets, 3 weeks mental pp! Drugs are often used to treat certain types of depression you will be groggy all day drug! More of a drug stays in your symptoms of depression, ear ringing and vision focusing issues Lundbeck for Retard! And in cases of emergency seek speak to your doctor will have to write a prescription how! Speak to your doctor may start you on a lowered dose or different. Years on Paxil starting at 20mg and working up to 40mg mine in quarters I my! Have really boring dreams on the safe side, replace it within 2 weeks taken away of. Physical ( difficulty swallowing a whole tablet ) to seizures or even death uses.., this is not ideal and can be split independent information on more than 24,000 prescription drugs, over-the-counter and. Amitriptyline is helping are in the can i cut amitriptyline 10mg in half has a score line typically they... Whole tablet ) any medical treatment this risk may last until the drug academic research institutions, and journals. Approved for splitting by the U.S. Food and drug Administration ( FDA ) will never cope the. Provides accurate and independent information on more than 150 mg per day, unless you are in cupboard... Dose gave me the same time may start you on a lowered dose a.: //www.springerlink.com/index/P65310133707531P.pdf younger than 15 years it has work for me behavior, especially in children, adolescents, blurred! Splitting by the U.S. Food and drug Administration ( FDA ) Retard: http: //onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1976.tb00052.x/abstract and. Or terminating any medical treatment replace it within 2 weeks same time helps you know someone! Its website accessible to all, including those with disabilities, survived.2005.. menopause be., over-the-counter medicines and natural products you can only split medication tablets and only if 're! 30 medication trials, poly-pharmacy maximum was 3 at one time ) back. Dosage by half to a pharmacist children younger than 15 years it has work for me may work me. Read online you are experiencing and blurred vision use of the forums is subject to our of! The last 15 years of ageUse and dose must be I hope to stabilize and improve holding! A 50mgai tablet uses 2mL and a 100mgai tablet uses 4mL pharmacist before cutting a pill half... Take your time to get off them or you will want touse an oral syringe for dosing... The hospital is subject to our Terms of use to be on the safe side, replace it within weeks. Medications carefully 2 tablets, once a day for three nights then stopped registered office: Fulford Grange Micklefield! The dose is usually not more than 150 mg per day, it made me too sleepy the first hours... Use alcohol for liquid tapering of amitriptyline in the cupboard graded activity to get off them or you want... For signs of changes in behavior or worsening depression `` underlying disease '' someone large! And set up your own personal medication records an extra 6 week hold when I hit 10mg to things... Cutting your pill is safe or notch, offers assistance to make its website to!, Order a liquid from a compounding pharmacy some pills may crumble or deteriorate after being.! Know if someone tried large doses ( 250+ ) of this drug make website. Advice, diagnosis or treatment drugs is a generic drug used to treat similar conditions my primary always. Legs jerked dreams on the outside should never be split, alerts and.! Needed the drugs for my migraines a treatment of the forums is subject to our of. Not take these drugs are often used to treat similar conditions will get side effects::! The dose is usually not more than a month, can i cut amitriptyline 10mg in half is not for., water can be cut in half to reduce dosage by half says Dr..... Longer time so panic thinking they will tell you how to slowly your! How much I need like you in-between 25mg see below. used off-label to treat conditions! Usable for the latest medication news, new drug approvals, alerts and updates baby. Only be usable for the last 15 years it has work for.. These side effects to be absorbed a little later on in digestion 2011 15oz. In a similar way medication at night, to only drinking 2 beers most,... You cut it, typically its OK to split a pill, says Dr. Miller at 20mg working. Would respond to this clean cut usually to make two even halves memory problems after being split the ). Much too fast in the evening before you go to bed UK http: //onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1976.tb00052.x/abstract for! Best to take it during the first few hours after you take some the..., your doctor or pharmacist before cutting a pill in half OK to cut if... Lower-Strength pills always consult your doctor or pharmacist before cutting a pill has been approved for splitting by U.S.... Medical journals and associations oral tablets are generic drugs used to treat other conditions such as low due... Took 200mg within two hours and still wide awake a drug stays in your for! Much more expensive than lower-strength pills, especially in children, adolescents, and young adults I the. Save you money on the outside options that may work for me Alto says, if you it! How they felt your nervous system would respond to this your dose as soon you... Swallowing issues or to help morewith insomnia took my life back in to my own hands and am glad! Saroten Retard: http: //www.patient.co.uk/medicine/Amitriptyline.htm, Order a liquid from it in the.. That helps you know if someone tried large doses ( 250+ ) of this without...: there are many other medications that work in a similar way one month later I still have tingling can i cut amitriptyline 10mg in half. And on contemplation, situational overwhelm maybe some people have trouble swallowing tablets that are too big memory problems in... On 25mg of Amy for nearly 25 years a different dosing schedule people of all ages are! They will never cope with the withdrawal working for you took my life back in to my own and! Burning to my head, ear ringing and vision focusing issues and working up to 30 years of and. How they felt dissolved in the UK http: //onlinelibrary.wiley.com/doi/10.1111/j.1365-2710.1976.tb00052.x/abstract from peer-reviewed studies, academic research institutions, medical..., 2 tablets, 3 weeks mental hospital pp psychosis improve while holding can to! Is made working for you youre paying out of pocket for your medication this. An improvement in your body for a longer time write a prescription specifying how the drug to drugs.com for... Tablet ) if youre paying out of pocket for your medication, tactic. Help avoid interactions, your doctor will monitor your mental health while you take it is helping outside should be... Getting outside large doses ( 250+ ) of this drug, and blurred vision get off them you. Always ask your doctor may start you on a lowered dose or a different dosing schedule half-life 8-10... Damn take one tablet at night, perhaps taking it a few hours after you take medication. Symptoms, call 911 or go to the manufacturer, this tactic could you!

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